221 Main – Restaurant & Cocktail House is a highly-rated steakhouse in St Joseph, MI, serving premium cuts of beef and an extensive cocktail menu. With a 4.4/5 star rating, this establishment offers a sophisticated dining experience in a charming downtown location.
Operator computes a Health score every night at 2 am HST. It is the one number that tells you if this shop is winning, losing, or steady. Here is how 221 Main - Restaurant & Cocktail House broke down on Apr 13, 2026.
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